{"id":827,"date":"2024-06-24T15:45:23","date_gmt":"2024-06-24T15:45:23","guid":{"rendered":"https:\/\/www.biomech.test.polimi.it\/?page_id=827"},"modified":"2024-06-26T08:57:22","modified_gmt":"2024-06-26T08:57:22","slug":"mimlab_home","status":"publish","type":"page","link":"https:\/\/www.biomech.test.polimi.it\/?page_id=827","title":{"rendered":"MimLab_Home"},"content":{"rendered":"\n<div class=\"wp-block-buttons alignfull is-content-justification-right is-layout-flex wp-container-core-buttons-is-layout-d445cf74 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-2-color has-text-color has-link-color wp-element-button\" href=\"https:\/\/www.biomech.test.polimi.it\/?page_id=827\">Home<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-2-color has-text-color has-link-color wp-element-button\">Research<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-2-color has-text-color has-link-color wp-element-button\" href=\"https:\/\/www.biomech.test.polimi.it\/?page_id=820\">People<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-2-color has-text-color has-link-color wp-element-button\">Facilities<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-2-color has-text-color has-link-color wp-element-button\" href=\"http:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/MimicsLab-Thesis-Projects.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Thesis<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-2-color has-text-color has-link-color wp-element-button\" href=\"mailto:marco.rasponi@polimi.it\">Contact Us<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#6c87cf\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1058\" class=\"wp-block-cover__image-background wp-image-756\" alt=\"\" src=\"http:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-scaled.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-scaled.jpg 2560w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-300x124.jpg 300w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-1024x423.jpg 1024w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-768x318.jpg 768w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-1536x635.jpg 1536w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/ooc-2048x847.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-text-color has-link-color has-large-font-size wp-elements-3f5398b143ef70a4fc89cbc63b529cdd\" style=\"color:#ffffff\"><strong>Organs-on-Chip and Microphysiological Systems<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-center has-text-color has-link-color wp-elements-1fb1c04da79ed391c213635a3608dae6\" style=\"color:#ffffff\">Our passion is to design and exploit microfluidic devices in the fields of basic biological research and translational pharmacological research. Ongoing projects are targeted at the following research areas: <strong>microfluidic bioreactors<\/strong> and <strong>organs-on-chip<\/strong><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull is-light\" style=\"min-height:550px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#6c87cf\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"3109\" height=\"1299\" class=\"wp-block-cover__image-background wp-image-1097\" alt=\"\" src=\"https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping.png\" data-object-fit=\"cover\" srcset=\"https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping.png 3109w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping-300x125.png 300w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping-1024x428.png 1024w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping-768x321.png 768w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping-1536x642.png 1536w, https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/mimiclab-trapping-2048x856.png 2048w\" sizes=\"auto, (max-width: 3109px) 100vw, 3109px\" \/><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-block-cover-is-layout-constrained\">\n<p class=\"has-text-align-center has-text-color has-link-color has-medium-font-size wp-elements-2aa9b4142efe0c8e1d1679781db3f711\" style=\"color:#ffffff\"><strong><strong>Microfluidic Bioreactors<\/strong><\/strong><\/p>\n\n\n\n<div class=\"wp-block-columns alignfull has-text-color has-link-color wp-elements-9706106a7108c25a2b22e271e0c03db3 is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\" style=\"color:#ffffff\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<ul class=\"wp-block-list\">\n<li>Performing single cell trapping, culture and analysis<\/li>\n\n\n\n<li>Implementing large scale automated microfluidic platforms for high-throughput parallelized screening<\/li>\n\n\n\n<li>Directing stem cells or iPS cells fate and differentiation through bio-chemical or physical stimuli<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-right is-layout-flex wp-container-core-buttons-is-layout-d445cf74 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-1-color has-text-color has-link-color has-border-color has-custom-color-1-border-color wp-element-button\" style=\"border-radius:10px\">Learn More<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-cover alignfull\" style=\"min-height:550px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\" style=\"background-color:#6e756a\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"372\" height=\"284\" class=\"wp-block-cover__image-background wp-image-1098\" alt=\"\" src=\"https:\/\/www.biomech.test.polimi.it\/wp-content\/uploads\/2024\/06\/heart-on-chip.gif\" data-object-fit=\"cover\"\/><div class=\"wp-block-cover__inner-container has-global-padding is-layout-constrained wp-block-cover-is-layout-constrained\">\n<p class=\"has-text-align-center has-medium-font-size\"><strong><strong>Organs-on-Chip<\/strong><\/strong><\/p>\n\n\n\n<div class=\"wp-block-columns alignfull is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<ul class=\"wp-block-list\">\n<li>Heart on a chip: mimicking human cardiac physiology and pathology (cardiac fibrosis, dystrophies) )in vitro through physical (e.g. mechanical &amp; electrical) or chemical (e.g. oxygen concentration gradients) stimulations<\/li>\n\n\n\n<li>Cartilage and joint on chip: recapitulating human cartilage, bone and joint models to study osteoarthritis<\/li>\n\n\n\n<li>Endothelial barriers on chip: unraveling the transport mechanisms through physiological barriers such as the blood-brain barrier or the gut endothelium<\/li>\n\n\n\n<li>Multicompartment microfluidic devices: the ability to generate multicellular tissues separated by neat interfaces allow to build complex human organ models (e.g. joint on chip, blood vessels on chip)<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-color-1-color has-text-color has-link-color has-border-color wp-element-button\" style=\"border-color:#2a2a2a;border-radius:10px\">Learn More<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\"><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-827","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=\/wp\/v2\/pages\/827","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=827"}],"version-history":[{"count":4,"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=\/wp\/v2\/pages\/827\/revisions"}],"predecessor-version":[{"id":1166,"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=\/wp\/v2\/pages\/827\/revisions\/1166"}],"wp:attachment":[{"href":"https:\/\/www.biomech.test.polimi.it\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=827"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}